CuI-catalyzed cycloisomerization of propargyl amides.
نویسندگان
چکیده
The synthesis of substituted dihydrooxazoles by the CuI-catalyzed cycloisomerization of terminal propargyl amides is reported. The reaction has been shown to have good substrate scope and experiments to delineate the mechanism have been performed. Substrates containing a benzylic methylene were oxidized to the ketone under the reaction conditions.
منابع مشابه
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 12 5 شماره
صفحات -
تاریخ انتشار 2014